From March 2015 till today up to 2500 patients consented to join our cohort and to help us improve diagnostics for critically ill patients and gain insight in healthy recovery.
With our team of researchers we aim to understand the concepts and mechanisms which underlie the complexities of organ failure in critically ill patients. We use clinical examination and critical care ultrasonography (CCUS) to explore and investigate the scientific hypotheses. Our goal is to answer knowledge gaps on clinical examination and CCUS to guide health care professionals in daily care.
The Simple Intensive Care Studies-I
The SICS-I ran from March 2015 until July 2017 and 1075 patients were included. Structured physical examination and CCUS of the heart and lungs were used to determine the clinical applicability of cardiac index measurements and to predict mortality. The protocol was published on clinicaltrials.gov and a design paper was published in the BMJ Open (links available on this website).
Currently, analysis of the data is ongoing and multiple manuscripts of our results will be published over the coming years.
The Simple Intensive Care Studies-II
The SICS-II started in May 2018 after the SICS-II pilot study. In SICS-II repeated measurements are introduced. Furthermore, ultrasonography of the inferior vena cava and kidney is added. The primary focus of SICS-II is on hemodynamic function and the development of organ failure. Multiple substudies are predefined. The protocol was published on clinicaltrials.gov and a design paper is accepted for publication in the JoVE. You can find the link and many other interesting content on the other pages on our website.
Currently, patient inclusion is ongoing 24/7 and other centres are welcome and invited to join.
Thanks for your interest in our research. Get in touch with us for any questions or comments regarding our work and publications. Would you like to run the Simple Intensive Care Studies in your department? We’d love to hear from you and we can help with implementing our protocol. Just fill in the form below.